View source for Template:Transient receptor potential channel modulators

{{Navbox
| name = Transient receptor potential channel modulators
| title = [[Transient receptor potential channel|{{abbr|TRP|Transient receptor potential}} channel]] [[ion channel modulator|modulator]]s
| state = {{{state<includeonly>|collapsed</includeonly>}}}
| listclass = hlist
| groupstyle = text-align:center;

  | group1 = {{abbrlink|TRPA|Transient receptor potential ankyrin channel}}<!--TRPA1, unless otherwise specified-->
  | list1 = {{Navbox|child
  | groupstyle = text-align:center;

    | group1 = Activators
    | list1 = 
* [[4-Hydroxynonenal]]
* [[4-Oxo-2-nonenal]]
* [[4,5-EET]]<!--4,5-Epoxy-8Z,11Z,14Z-eicosatrienoic acid-->
* [[12S-HpETE]]<!--12S-Hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid-->
* [[15-Deoxy-Δ12,14-prostaglandin J2|15-Deoxy-Δ<sup>12,14</sup>-prostaglandin J2]]
* [[Sanshool|α-Sanshool]] ([[ginger]], [[Sichuan pepper|Sichuan]] and [[melegueta pepper]]s)
* [[Acrolein]]
* [[Allicin]] ([[garlic]])
* [[Allyl isothiocyanate]] ([[mustard plant|mustard]], [[radish]], [[horseradish]], [[wasabi]])
* [[AM404]]
* [[Bradykinin]]
* [[Cannabichromene]] ([[cannabis]])
* [[Cannabidiol]] ([[cannabis]])
* [[Cannabigerol]] ([[cannabis]])
* [[Cinnamaldehyde]] ([[cinnamon]])
* [[CR gas|CR gas (dibenzoxazepine; DBO)]]
* [[CS gas|CS gas (2-chlorobenzal malononitrile)]]
* [[Curcumin]] ([[turmeric]])
* [[Dehydroligustilide]] ([[celery]])<!--bimodal-->
* [[Diallyl disulfide]]
* [[Dicentrine]] (''[[Lindera]]'' spp.)
* [[Farnesyl thiosalicylic acid]]
* [[Formalin]]
* [[Gingerol]]s ([[ginger]])
* [[Hepoxilin A3]]<!--8R/S-Hydroxy-11,12-oxido-5Z,9E,14Z-eicosatrienoic acid-->
* [[Hepoxilin B3]]<!--10R/S-Hydroxy-11,12-oxido-5Z,8Z,14Z-eicosatrienoic acid-->
* [[Hydrogen peroxide]]
* [[Icilin]]
* [[Isothiocyanate]]
* [[Ligustilide]] ([[celery]], ''[[Angelica acutiloba]]'')
* [[Linalool]] ([[Sichuan pepper]], [[thyme]])
* [[Methylglyoxal]]
* [[Methyl salicylate]] ([[wintergreen]])
* [[N-Methylmaleimide]]
* [[Nicotine]] ([[tobacco]])
* [[Oleocanthal]] ([[olive oil]])
* [[Paclitaxel]] ([[Pacific yew]])
* [[Paracetamol|Paracetamol (acetaminophen)]]
* [[PF-4840154]]
* [[Phenacyl chloride]]
* [[Polygodial]] ([[Dorrigo pepper]])
* [[Shogaol]]s ([[ginger]], [[Sichuan pepper|Sichuan]] and [[melegueta pepper]]s)
* [[Tear gas]]es
* [[Tetrahydrocannabinol]] ([[cannabis]])
* [[Thiopropanal S-oxide]] ([[onion]])
* [[Umbellulone]] (''[[Umbellularia californica]]'')
* [[WIN 55,212-2]]

    | group2 = Blockers
    | list2 = 
* [[Dehydroligustilide]] ([[celery]])<!--bimodal-->
* [[Nicotine]] ([[tobacco]])<!--bimodal-->
* [[Ruthenium red]]

  }}

  | group2 = {{abbrlink|TRPC|Transient receptor potential canonical channel}}
  | list2 = {{Navbox|child
  | groupstyle = text-align:center;

    | group1 = Activators
    | list1 = 
* [[Adhyperforin]] ([[St John's wort]])<!--TRPC6-->
* [[Diacyl glycerol]]<!--TRPC3, TRPC6, and TRPC7-->
* [[GSK1702934A]]<!--TRPC3-->
* [[Hyperforin]] ([[St John's wort]])<!--TRPC6-->
* [[Substance P]]<!--TRPC3, TRPC7-->

    | group2 = Blockers
    | list2 = 
* [[3′-5-Dichlorodiphenylamine-2-carboxylic acid|DCDPC]]<!--TRPC6-->
* [[Dehydroepiandrosterone sulfate|DHEA-S]]<!--TRPC5-->
* [[Flufenamic acid]]<!--TRPC6-->
* [[GSK417651A]]<!--TRPC3-->
* [[GSK2293017A]]<!--TRPC3-->
* [[Meclofenamic acid]]<!--TRPC6-->
* [[N-(p-amylcinnamoyl)anthranilic acid]]<!--TRPC6-->
* [[Niflumic acid]]<!--TRPC6-->
* [[Pregnenolone sulfate]]<!--TRPC5-->
* [[Progesterone]]<!--TRPC5-->
* [[Pyr3]]<!--TRPC3-->
* [[Tolfenamic acid]]<!--TRPC6-->

  }}

  | group3 = {{abbrlink|TRPM|Transient receptor potential melastatin channel}}
  | list3 = {{Navbox|child
  | groupstyle = text-align:center;

    | group1 = Activators
    | list1 = 
* [[Adenosine diphosphate ribose|ADP-ribose]]<!--TRPM2-->
* [[BCTC (drug)|BCTC]]<!--TRPM8-->
* [[Calcium]] (intracellular)<!--TRPM4, TRPM5-->
* [[Cold]]<!--TRPM8-->
* [[Coolact P]]<!--TRPM8-->
* [[Cooling Agent 10]]<!--TRPM8-->
* [[CPS-369]]<!--TRPM8-->
* [[Eucalyptol]] ([[eucalyptus]])<!--TRPM8-->
* [[Frescolat MGA]]<!--TRPM8-->
* [[Frescolat ML]]<!--TRPM8-->
* [[Geraniol]]<!--TRPM8-->
* [[Hydroxycitronellal]]<!--TRPM8-->
* [[Icilin]]<!--TRPM8-->
* [[Linalool]]<!--TRPM8-->
* [[Menthol]] ([[Mentha|mint]])<!--TRPM8-->
* [[PMD 38]]<!--TRPM8-->
* [[Pregnenolone sulfate]]<!--TRPM3-->
* [[Rutamarin]] (''[[Ruta graveolens]]'')<!--TRPM5-->
* [[Steviol glycoside]]s (e.g., [[stevioside]]) (''[[Stevia rebaudiana]]'')<!--TRPM5-->
* Sweet [[taste|tastant]]s (e.g., [[glucose]], [[fructose]], [[sucrose]]; indirectly)<!--TRPM5-->
* [[Thio-BCTC]]<!--TRPM8-->
* [[WS-3]]<!--TRPM8-->
* [[WS-12]]<!--TRPM8-->
* [[WS-23]]<!--TRPM8-->

    | group2 = Blockers
    | list2 = 
* [[Capsazepine]]<!--TRPM8-->
* [[Clotrimazole]]<!--TRPM5-->
* [[3′-5-Dichlorodiphenylamine-2-carboxylic acid|DCDPC]]<!--TRPM2, TRPM3-->
* [[Flufenamic acid]]<!--TRPM2, TRPM3, TRPM4, TRPM5-->
* [[Meclofenamic acid]]<!--TRPM2, TRPM3-->
* [[Mefenamic acid]]<!--Selective for TRPM3 only-->
* [[N-(p-amylcinnamoyl)anthranilic acid]]<!--TRPM2, TRPM8-->
* [[Nicotine]] ([[tobacco]])<!--TRPM5-->
* [[Niflumic acid]]<!--TRPM3-->
* [[Ruthenium red]]<!--TRPM6, TRPM8-->
* [[Rutamarin]] (''[[Ruta graveolens]]'')<!--TRPM8-->
* [[Tolfenamic acid]]<!--TRPM2, TRPM3-->
* [[Triphenylphosphine oxide|TPPO]]<!--TRPM5-->

  }}

  | group4 = {{abbrlink|TRPML|Transient receptor potential mucolipin channel}}
  | list4 = {{Navbox|child
  | groupstyle = text-align:center;

    | group1 = Activators
    | list1 = 
* [[MK6-83]]<!--5-methyl-N-(2-piperidin-1-ylphenyl)thiophene-2-sulphonamide-->
* [[Phosphatidylinositol 3,5-bisphosphate|PI(3,5)P<sub>2</sub>]]
* [[SF-22]]<!--5-chloro-N-(2-piperidin-1-ylphenyl)thiophene-2-sulphonamide-->

    | group2 = Blockers
    | list2 = 

  }}

  | group6 = {{abbrlink|TRPP|Transient receptor potential polycystin channel}}
  | list6 = {{Navbox|child
  | groupstyle = text-align:center;

    | group1 = Activators
    | list1 = 
* [[Triptolide]] (''[[Tripterygium wilfordii]]'')

    | group2 = Blockers
    | list2 = 
* [[Ruthenium red]]<!--TRPP3-->

  }}

  | group7 = {{abbrlink|TRPV|Transient receptor potential vanilloid channel}}<!--TRPV1, unless otherwise specified-->
  | list7 = {{Navbox|child
  | groupstyle = text-align:center;

    | group1 = Activators
    | list1 = 
* [[2-Aminoethoxydiphenyl borate|2-APB]]<!--TRPV1, TRPV2, and TRPV3-->
* [[5',6'-Epoxyeicosatrienoic acid|5',6'-EET]]<!--TRPV4-->
* [[9-Hydroxyoctadecadienoic acid|9-HODE]]<!--9(S/R)-Hydroxy-10(E),12(Z)-octadecadienoic acid-->
* [[9-oxoODE]]
* [[12S-HETE]]<!--12S-Hydroxy-5Z,8Z,10E,12S,14Z-eicosatetraenoic acid-->
* [[12S-HpETE]]<!--12S-Hydroperoxy-5Z,8Z,10E,14Z-eicosatetraenoic acid-->
* [[13-Hydroxyoctadecadienoic acid|13-HODE]]<!--13(S/R)-Hydroxy-9Z,11E-octadecadienoic acid-->
* [[13-oxoODE]]
* [[20-Hydroxyeicosatetraenoic acid|20-HETE]]<!--20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid-->
* [[Sanshool|α-Sanshool]] ([[ginger]], [[Sichuan pepper|Sichuan]] and [[melegueta pepper]]s)
* [[Allicin]] ([[garlic]])
* [[AM404]]
* [[Anandamide]]
* [[Bisandrographolide]] (''[[Andrographis paniculata]]'')<!--TRPV4, not TRPV1, TRPV2, or TRPV3-->
* [[Camphor]] ([[camphor laurel]], [[rosemary]], [[camphorweed]], [[African blue basil]], [[Ocimum kilimandscharicum|camphor basil]])<!--TRPV1 and TRPV3-->
* [[Cannabidiol]] ([[cannabis]])<!--TRPV1, TRPV2, and TRPV3-->
* [[Cannabidivarin]] ([[cannabis]])<!--TRPV4-->
* [[Capsaicin]] ([[chili pepper]])
* [[Carvacrol]] ([[oregano]], [[thyme]], [[Lepidium|pepperwort]], [[wild bergamot]], others)<!--TRPV1 and TRPV3-->
* [[Dehydroepiandrosterone|DHEA]]
* [[Diacyl glycerol]]<!--TRPV4-->
* [[Dihydrocapsaicin]] ([[chili pepper]])
* [[Estradiol]]<!--TRPV1-->
* [[Eugenol]] ([[basil]], [[clove]])<!--TRPV1 and TRPV3-->
* [[Evodiamine]] (''[[Euodia ruticarpa]]'')
* [[Gingerol]]s ([[ginger]])
* [[GSK1016790A]]<!--TRPV1, TRPV4-->
* [[Heat]]<!--TRPV1, TRPV3, TRPV4-->
* [[Hepoxilin A3]]<!--8R/S-Hydroxy-11,12-oxido-5Z,9E,14Z-eicosatrienoic acid-->
* [[Hepoxilin B3]]<!--10R/S-Hydroxy-11,12-oxido-5Z,8Z,14Z-eicosatrienoic acid-->
* [[Homocapsaicin]] ([[chili pepper]])
* [[Homodihydrocapsaicin]] ([[chili pepper]])
* [[Incensole]] ([[incense]])<!--TRPV3, not TRPV1-->
* [[Lysophosphatidic acid]]
* Low [[pH]] (acidic conditions)
* [[Menthol]] ([[Mentha|mint]])<!--TRPV3, not TRPV1-->
* [[N-Arachidonoyl dopamine]]
* [[N-Oleoyldopamine]]
* [[N-Oleoylethanolamide]]
* [[Nonivamide|Nonivamide (PAVA)]] ([[PAVA spray]])
* [[Nordihydrocapsaicin]] ([[chili pepper]])
* [[Paclitaxel]] ([[Pacific yew]])<!--TRPV4, not TRPV1-->
* [[Paracetamol|Paracetamol (acetaminophen)]]
* [[Phorbol esters]] (e.g., [[4α-phorbol 12,13-didecanoate|4α-PDD]])<!--TRPV4-->
* [[Piperine]] ([[black pepper]], [[long pepper]])
* [[Polygodial]] ([[Dorrigo pepper]])
* [[Probenecid]]<!--TRPV2-->
* [[Proton]]s
* [[Rutamarin]] (''[[Ruta graveolens]]'')
* [[Resiniferatoxin]] (RTX) (''[[Euphorbia resinifera]]/[[Euphorbia poissonii|pooissonii]]'')
* [[Shogaol]]s ([[ginger]], [[Sichuan pepper|Sichuan]] and [[melegueta pepper]]s)
* [[Tetrahydrocannabivarin]] ([[cannabis]])<!--TRPV3, TRPV4-->
* [[Thymol]] ([[thyme]], [[oregano]])<!--TRPV1 and TRPV3-->
* [[Tinyatoxin]] (''[[Euphorbia resinifera]]/[[Euphorbia poissonii|pooissonii]]'')
* [[Tramadol]]
* [[Vanillin]] ([[vanilla]])<!--TRPV1 and TRPV3-->
* [[Zucapsaicin]]

    | group2 = Blockers
    | list2 = 
* [[Spinasterol|α-Spinasterol]] (''[[Vernonia|Vernonia tweediana]]'')<!--TRPV1-->
* [[AMG-517]]<!--TRPV1-->
* [[Asivatrep]]<!--TRPV1-->
* [[BCTC (drug)|BCTC]]<!--TRPV1-->
* [[Cannabigerol]] ([[cannabis]])<!--TRPV4-->
* [[Cannabigerolic acid]] ([[cannabis]])<!--TRPV3, TRPV4-->
* [[Cannabigerovarin]] ([[cannabis]])<!--TRPV3, TRPV4-->
* [[Cannabinol]] ([[cannabis]])<!--TRPV4-->
* [[Capsazepine]]<!--TRPV1-->
* [[3′-5-Dichlorodiphenylamine-2-carboxylic acid|DCDPC]]<!--TRPV4-->
* [[Dehydroepiandrosterone|DHEA]]<!--TRPV1-->
* [[Dehydroepiandrosterone sulfate|DHEA-S]]<!--TRPV1-->
* [[Flufenamic acid]]<!--TRPV4-->
* [[GRC-6211]]<!--TRPV1-->
* [[HC-067047]]<!--TRPV4-->
* [[Lanthanum]]<!--TRPV2-->
* [[Meclofenamic acid]]<!--TRPV4-->
* [[N-(p-amylcinnamoyl)anthranilic acid]]<!--TRPV1-->
* [[NGD-8243]]<!--TRPV1-->
* [[Niflumic acid]]<!--TRPV4-->
* [[Pregnenolone sulfate]]<!--TRPV1-->
* [[RN-1734]]<!--TRPV4-->
* [[RN-9893]]<!--TRPV4-->
* [[Ruthenium red]]<!--TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6-->
* [[SB-705498]]<!--TRPV1-->
* [[Tolfenamic acid]]<!--TRPV4-->

  }}

| below = '''''See also:''' [[Template:Receptor modulators|Receptor/signaling modulators]] • [[Template:Ion channel modulators|Ion channel modulators]]''

}}<noinclude>
{{collapsible option}}
[[Category:Drug templates by receptor, channel, or pump]]
</noinclude>