View source for Template:Opioid receptor modulators

{{Navbox
 | name = Opioid receptor modulators
 | title = [[Opioid receptor]] [[receptor modulator|modulator]]s
 | state = {{{state<includeonly>|collapsed</includeonly>}}}
 | listclass = hlist
 | groupstyle = text-align:center;

 | group1 = {{abbrlink|MOR|μ-Opioid receptor}}
 | list1 =
* '''Agonists''' ''(abridged; see [[List of opioids|here]] for a full list)''''':'''<!--Please add MOR agonists sparingly! Preferably notable, marketed, and/or atypical MOR agonists only.--> [[3-HO-PCP]]
* [[7-Acetoxymitragynine]]
* [[7-Hydroxymitragynine]]
* [[ψ-Akuammigine]]
* [[α-Chlornaltrexamine]]<!--Irreversible-->
* [[alpha-Narcotine|α-Narcotine]]
* [[Acetyldihydrocodeine]]
* [[Acetylfentanyl]]
* [[Acrylfentanyl]]
* [[Adrenorphin|Adrenorphin (metorphamide)]]
* [[AH-7921]]
* [[Akuammicine]]
* [[Akuammidine]]
* [[Alfentanil]]
* [[Anileridine]]
* [[Apparicine]]
* [[β-Endorphin]]
* [[Bovine adrenal medullary peptide-12P|BAM-12P]]
* [[Bovine adrenal medullary peptide-18P|BAM-18P]]
* [[Bovine adrenal medullary peptide-22P|BAM-22P]]
* [[Benzhydrocodone]]
* [[Benzylmorphine]]
* [[Bezitramide]]
* [[Biphalin]]
* [[BU08070]]
* [[Buprenorphine]]
* [[Butorphan]]
* [[Butorphanol]]
* [[Butyrfentanyl]]
* [[BW-373U86]]
* [[Carfentanil]]
* [[Casokefamide]]
* [[Cebranopadol]]
* [[Chloroxymorphamine]]<!--Irreversible-->
* [[Codeine]]
* [[DADLE]]
* [[DAMGO|DAMGO (DAGO)]]
* [[Dermorphin]]
* [[Desmetramadol|Desmetramadol (desmethyltramadol)]]
* [[Desomorphine]]
* [[Dextromoramide]]
* [[Dextropropoxyphene|Dextropropoxyphene (propoxyphene)]]
* [[Dezocine]]
* [[Dimenoxadol]]
* [[Dimethylaminopivalophenone]]
* [[Eluxadoline]]
* [[Heroin|Diamorphine (heroin)]]
* [[Dihydrocodeine]]
* [[Dihydroetorphine]]
* [[Dihydromorphine]]
* [[Diphenoxylate]]
* [[Dipipanone]]
* [[Dynorphin A]]
* [[Embutramide]]
* [[Endomorphin-1]]
* [[Endomorphin-2]]
* [[Eseroline]]
* [[Ethylmorphine]]
* [[Etorphine]]
* [[Fentanyl]]
* [[Fluorophen]]
* [[Frakefamide]]
* [[Furanylfentanyl]]
* [[Hemorphin-4]]
* [[Herkinorin]]
* [[Hodgkinsine]]
* [[Hydrocodone]]
* [[Hydromorphinol]]
* [[Hydromorphone]]
* [[IBNtxA]]
* [[Ketamine]]
* [[Ketobemidone]]
* [[Mitragyna speciosa|Kratom]]
* [[Laudanosine]]
* [[Lefetamine]]
* [[Leu-enkephalin]]
* [[Levacetylmethadol]]
* [[Levomethorphan]]
* [[Levorphanol]]
* [[Lexanopadol]]
* [[Loperamide]]
* [[Loxicodegol]]
* [[Matrine]]
* [[Meptazinol]]
* [[Met-enkephalin|Met-enkephalin (metenkefalin)]]
* [[Methadone]]
* [[Metkefamide]]
* [[Metopon]]
* [[Mitragynine]]
* [[Mitragynine pseudoindoxyl]]
* [[Morphiceptin]]
* [[Morphine]]
* [[Nalbuphine]]
* [[Nalbuphine sebacate]]
* [[Naloxone benzoylhydrazone|NalBzOH]]
* [[Nalmexone]]
* [[Naltalimide]]
* [[Neopine]]
* [[NFEPP]]
* [[Nicocodeine]]
* [[Nicodicodeine]]
* [[Nicomorphine]]
* [[NKTR-181]]
* [[Norketamine]]
* [[Octreotide]]
* [[Oliceridine]]
* [[Oxymorphone-3-methoxynaltrexonazine|OM-3-MNZ]]
* [[Oripavine]]
* [[Oxycodone]]
* [[Oxymorphazone]]<!--Irreversible-->
* [[Oxymorphonazine]]<!--Irreversible-->
* [[Oxymorphone]]
* [[Oxymorphone phenylhydrazone]]<!--Irreversible-->
* [[Oxymorphone p-nitrophenylhydrazone|OxyPNPH]]<!--Irreversible-->
* ''[[Papaver somniferum]]'' ([[opium]])
* [[Pentazocine]]
* [[Pericine]]
* [[Pethidine|Pethidine (meperidine)]]
* [[Phenazocine]]
* [[Phencyclidine]]
* [[Piminodine]]
* [[Piritramide]]
* [[PL-017]]
* [[Prodine]]
* [[Propiram]]
* [[PZM21]]
* [[Racemethorphan]]
* [[Racemorphan]]
* [[Remifentanil]]
* [[Salsolinol]]
* [[SC-17599]]
* [[Sinomenine]]
* [[Sufentanil]]
* [[Tapentadol]]
* [[Tetrahydropapaveroline]]
* [[TH-030418]]
* [[Thebaine]]
* [[Thienorphine]]
* [[Tianeptine]]
* [[Tilidine]]
* [[Tramadol]]
* [[Trimebutine]]
* [[TRIMU 5]]
* [[TRV734]]
* [[Tubotaiwine]]
* [[U-47700]]
* [[Valorphin]]
* [[Viminol]]
* [[Xorphanol]]

* '''PAMs:''' [[BMS-986121]]
* [[BMS-986122]]

* '''Antagonists:''' [[Picenadol|(3S,4S)-Picenadol]]
* [[Viminol|2-(S)-N,N-(R)-Viminol]]
* [[3CS-nalmefene]]<!--3-Carboxamido seco-nalmefene; https://www.ncbi.nlm.nih.gov/pubmed/28844812-->
* [[4-Caffeoyl-1,5-quinide]]
* [[4′-Hydroxyflavanone]]
* [[4',7-Dihydroxyflavone]]
* [[6β-Naltrexol]]
* [[6β-Naltrexol-d4]]
* [[18-Methoxycoronaridine|18-MC]]
* [[alpha-Gliadin|α-Gliadin]]
* [[β-Chlornaltrexamine]]<!--Irreversible-->
* [[beta-Funaltrexamine|β-Funaltrexamine]]<!--Irreversible-->
* [[Akuammine]]
* [[Alvimopan]]
* [[AM251|AM-251]]
* [[Apigenin]]
* [[AT-076]]
* [[Axelopran]]
* [[Bevenopran]]
* [[Catechin]]
* [[Catechin gallate]]
* [[Clocinnamox]]<!--Irreversible-->
* [[CTAP]]
* [[CTOP]]
* [[Cyclofoxy]]<!--6-Deoxy-6β-fluoronaltrexone; MOR- and KOR-selective antagonist radiotracer; PMID: 2825063-->
* [[Cyprodime]]
* [[Diacetylnalorphine]]
* [[Diprenorphine]]
* [[Epicatechin gallate|ECG]]
* [[Epigallocatechin|EGC]]
* [[Epicatechin]]
* [[Eptazocine]]
* [[Gemazocine]]
* [[Ginsenoside R]]
* [[Hyperoside]]
* [[Ibogaine]]
* [[Levallorphan]]
* [[Lobeline]]
* [[LY-255582]]
* [[LY-2196044]]
* [[Methocinnamox]]<!--Irreversible-->
* [[Methylnaltrexone]]
* [[Methylsamidorphan chloride]]
* [[Naldemedine]]
* [[Nalmefene]]
* [[Nalodeine|Nalodeine (N-allylnorcodeine)]]
* [[Nalorphine]]
* [[Nalorphine dinicotinate]]
* [[Naloxazone]]<!--Irreversible-->
* [[Naloxegol]]
* [[Naloxol]]
* [[Naloxonazine]]<!--Irreversible-->
* [[Naloxone]]
* [[Naltrexazone]]<!--Irreversible-->
* [[Naltrexonazine]]<!--Irreversible-->
* [[Naltrexone]]
* [[Naltrindole]]
* [[Naringenin]]
* [[Noribogaine]]
* [[Oxilorphan]]
* [[Pawhuskin A]]
* [[Rimonabant]]
* [[Quadazocine]]
* [[Samidorphan]]
* [[Taxifolin]]

* '''Unknown/unsorted:''' [[Cannabidiol]]<!--PMID: 16489449-->
* [[Coronaridine]]
* [[Cyproterone acetate]]
* [[Dihydroakuuamine]]
* [[Tabernanthine]]
* [[Tetrahydrocannabinol]]<!--PMID: 16489449-->

 | group2 = {{abbrlink|DOR|δ-opioid receptor}}
 | list2 =
* '''Agonists:''' [[3CS-nalmefene]]<!--3-Carboxamido seco-nalmefene; https://www.ncbi.nlm.nih.gov/pubmed/28844812-->
* [[6'-Guanidinonaltrindole|6'-GNTI]]
* [[7-Spiroindanyloxymorphone|7-SIOM]]
* [[ADL-5747|ADL-5747 (PF-04856881)]]
* [[ADL-5859]]
* [[Alazocine|Alazocine (SKF-10047)]]
* [[Amoxapine]]
* [[AR-M100390|AR-M100390 (ARM390)]]
* [[AZD2327]]
* [[β-Endorphin]]
* [[Bovine adrenal medullary peptide-18P|BAM-18P]]
* [[Biphalin]]
* [[BU-48]]
* [[Butorphan]]
* [[Butorphanol]]
* [[BW-373U86]]
* [[Casokefamide]]
* [[Cebranopadol]]
* [[Codeine]]
* [[Cyclazocine]]
* [[DADLE]]
* [[Deltorphin|Deltorphin A]]
* [[Deltorphin I]]
* [[Deltorphin II]]
* [[Desmethylclozapine]]
* [[Desmetramadol|Desmetramadol (desmethyltramadol)]]
* [[Dezocine]]
* [[Heroin|Diamorphine (heroin)]]
* [[Dihydroetorphine]]
* [[Dihydromorphine]]
* [[DPDPE]]
* [[DPI-221]]
* [[DPI-3290]]
* [[(D-Ser2, Leu5, Thr6)-Enkephalin|DSLET]]
* [[Ethylketazocine]]
* [[Etorphine]]
* [[Fentanyl]]
* [[Fentanyl isothiocyanate|FIT]]<!--Irreversible-->
* [[Fluorophen]]
* [[Hemorphin-4]]
* [[Hydrocodone]]
* [[Hydromorphone]]
* [[Ibogaine]]
* [[Isomethadone]]
* [[JNJ-20788560]]
* [[KNT-127]]<!--Antidepressant-like and antinociceptive effects without convulsions-->
* [[Mitragyna speciosa|Kratom]]
* [[Laudanosine]]
* [[Leu-enkephalin]]
* [[Levomethorphan]]
* [[Levorphanol]]
* [[Lexanopadol]]
* [[Lofentanil]]
* [[Met-enkephalin|Met-enkephalin (metenkefalin)]]
* [[Metazocine]]
* [[Metkefamide]]
* [[Mitragynine]]
* [[Mitragynine pseudoindoxyl]]
* [[Morphine]]
* [[N-Phenethyl-14-ethoxymetopon]]
* [[Norbuprenorphine]]
* [[Naloxone benzoylhydrazone|NalBzOH]]
* [[Oripavine]]
* [[Oxycodone]]
* [[Oxymorphone]]
* [[Pethidine|Pethidine (meperidine)]]
* [[Proglumide]]
* [[Racemethorphan]]
* [[Racemorphan]]
* [[RWJ-394674]]
* [[Samidorphan]]
* [[SB-235863]]
* [[SNC-80]]
* [[SNC-162]]
* [[TAN-67|TAN-67 (SB-205,607)]]
* [[TH-030418]]
* [[Thebaine]]
* [[Thiobromadol|Thiobromadol (C-8813)]]
* [[Tonazocine]]
* [[Tramadol]]
* [[TRV250]]
* [[Xorphanol]]
* [[Zenazocine]]

* '''Antagonists:''' [[4',7-Dihydroxyflavone]]
* [[Naltrindole-5'-isothiocyanate|5'-NTII]]<!--Irreversible-->
* [[6β-Naltrexol]]
* [[6β-Naltrexol-d4]]
* [[alpha-Santolol|α-Santolol]]
* [[β-Chlornaltrexamine]]<!--Irreversible-->
* [[Apigenin]]
* [[AT-076]]
* [[Axelopran]]
* [[Bevenopran]]
* [[7-Benzylidenenaltrexone|BNTX]]<!--Selective δ1 antagonist-->
* [[Catechin]]
* [[Catechin gallate]]
* [[Clocinnamox]]
* [[Diacetylnalorphine]]
* [[Diprenorphine]]
* [[Epicatechin gallate|ECG]]
* [[Epigallocatechin|EGC]]
* [[Eluxadoline]]
* [[Epicatechin]]
* [[ICI-154129]]
* [[ICI-174864]]
* [[LY-255582]]
* [[LY-2196044]]
* [[Methylnaltrexone]]
* [[Methylnaltrindole]]<!--MeNTI; DOR-selective antagonist radiotracer-->
* [[N-Benzylnaltrindole]]
* [[Nalmefene]]
* [[Nalorphine]]
* [[Naltrexone]]
* [[Naltriben]]<!--Selective δ2 antagonist-->
* [[Naltrindole]]
* [[Naloxone]]
* [[Naringenin]]
* [[Noribogaine]]
* [[Pawhuskin A]]
* [[Quadazocine]]
* [[SDM25N]]
* [[SoRI-9409]]
* [[Taxifolin]]
* [[Thienorphine]]

* '''Unknown/unsorted:''' [[18-Methoxycoronaridine|18-MC]]
* [[Cannabidiol]]<!--PMID: 16489449-->
* [[Coronaridine]]
* [[Cyproterone acetate]]
* [[Tabernanthine]]
* [[Tetrahydrocannabinol]]<!--PMID: 16489449-->

 | group3 = {{abbrlink|KOR|κ-Opioid receptor}}
 | list3 =
* '''Agonists:''' [[3CS-nalmefene]]<!--3-Carboxamido seco-nalmefene; https://www.ncbi.nlm.nih.gov/pubmed/28844812-->
* [[6'-Guanidinonaltrindole|6'-GNTI]]<!--Biased agonist-->
* [[8-Carboxamidocyclazocine|8-CAC]]
* [[18-Methoxycoronaridine|18-MC]]
* [[14-Methoxymetopon]]
* [[β-Chlornaltrexamine]]
* [[beta-Funaltrexamine|β-Funaltrexamine]]
* [[Adrenorphin|Adrenorphin (metorphamide)]]
* [[Akuuamicine]]
* [[Alazocine|Alazocine (SKF-10047)]]
* [[Allomatrine]]
* [[Apadoline]]
* [[Asimadoline]]
* [[Bovine adrenal medullary peptide-12P|BAM-12P]]
* [[Bovine adrenal medullary peptide-18P|BAM-18P]]
* [[Bovine adrenal medullary peptide-22P|BAM-22P]]
* [[Big dynorphin]]
* [[Bremazocine]]
* [[BRL-52537]]
* [[Butorphan]]
* [[Butorphanol]]
* [[BW-373U86]]
* [[Cebranopadol]]
* [[Ciprefadol]]
* [[CR665]]
* [[Cyclazocine]]
* [[Cyclorphan]]
* [[Cyprenorphine]]
* [[Desmetramadol|Desmetramadol (desmethyltramadol)]]
* [[Heroin|Diamorphine (heroin)]]
* [[Diacetylnalorphine]]
* [[Difelikefalin]]
* [[Dihydroetorphine]]
* [[Dihydromorphine]]
* [[Diprenorphine]]
* [[Dynorphin A]]
* [[Dynorphin B|Dynorphin B (rimorphin)]]
* [[Eluxadoline]]
* [[Enadoline]]
* [[Eptazocine]]
* [[Erinacine E]]
* [[Ethylketazocine]]
* [[Etorphine]]
* [[Fedotozine]]
* [[Fentanyl]]
* [[Gemazocine]]
* [[GR-89696]]<!--First KOR-selective agonist radiotracer-->
* [[GR-103545]]<!--(–)-Isomer of GR-89696 (active isomer); first-in-humans KOR-selective agonist radiotracer-->
* [[Hemorphin-4]]
* [[Herkinorin]]
* [[HS665]]
* [[Hydromorphone]]
* [[HZ-2]]
* [[Ibogaine]]
* [[ICI-199,441]]
* [[ICI-204,448]]
* [[Ketamine]]
* [[Ketazocine]]
* [[Laudanosine]]
* [[Leumorphin|Leumorphin (dynorphin B-29)]]
* [[Levallorphan]]
* [[Levomethorphan]]
* [[Levorphanol]]
* [[Lexanopadol]]
* [[Lofentanil]]
* [[LPK-26]]
* [[Lufuradom]]
* [[Matrine]]
* [[MB-1C-OH]]
* [[Menthol]]
* [[Metazocine]]
* [[Metkefamide]]
* [[Mianserin]]
* [[Mirtazapine]]
* [[Morphine]]
* [[Moxazocine]]
* [[MR-2034]]
* [[N-MPPP]]
* [[Nalbuphine]]
* [[Nalbuphine sebacate]]
* [[Naloxone benzoylhydrazone|NalBzOH]]
* [[Nalfurafine]]
* [[Nalmefene]]
* [[Nalodeine|Nalodeine (N-allylnorcodeine)]]
* [[Nalorphine]]
* [[Naltriben]]
* [[Niravoline]]
* [[Norbuprenorphine]]
* [[Norbuprenorphine-3-glucuronide]]
* [[Noribogaine]]<!--Biased agonist-->
* [[Norketamine]]
* [[Oripavine]]
* [[Oxilorphan]]
* [[Oxycodone]]
* [[Pentazocine]]
* [[Pethidine|Pethidine (meperidine)]]
* [[Phenazocine]]
* [[Proxorphan]]
* [[Racemethorphan]]
* [[Racemorphan]]
* [[RB-64]]<!--Biased agonist-->
* [[Salvinorin A]] ([[Salvia divinorum|salvia]])
* [[Salvinorin B ethoxymethyl ether]]
* [[Salvinorin B methoxymethyl ether]]
* [[Samidorphan]]
* [[Spiradoline|Spiradoline (U-62,066)]]
* [[TH-030418]]
* [[Thienorphine]]
* [[Tifluadom]]
* [[Tricyclic antidepressant]]s (e.g., [[amitriptyline]], [[desipramine]], [[imipramine]], [[nortriptyline]])
* [[U-50,488]]
* [[U-54,494A]]
* [[U-69,593]]
* [[Xorphanol]]

* '''Antagonists:''' [[4′-Hydroxyflavanone]]
* [[4',7-Dihydroxyflavone]]
* [[5'-Guanidinonaltrindole|5'-GNTI]]
* [[6'-Guanidinonaltrindole|6'-GNTI]]<!--Biased agonist-->
* [[6β-Naltrexol]]
* [[6β-Naltrexol-d4]]
* [[β-Chlornaltrexamine]]<!--Irreversible-->
* [[Buprenorphine/samidorphan]]
* [[Amentoflavone]]
* [[5'-Acetamidinoethylnaltrindole|ANTI]]
* [[Apigenin]]
* [[Arodyne]]
* [[AT-076]]
* [[Axelopran]]
* [[AZ-MTAB]]
* [[Binaltorphimine]]
* [[BU09059]]
* [[Buprenorphine]]
* [[Catechin]]
* [[Catechin gallate]]
* [[CERC-501|CERC-501 (LY-2456302)]]
* [[Clocinnamox]]
* [[Cyclofoxy]]<!--6-Deoxy-6β-fluoronaltrexone; MOR- and KOR-selective antagonist radiotracer; PMID: 2825063-->
* [[Dezocine]]
* [[DIPPA]]<!--Irreversible-->
* [[Epigallocatechin|EGC]]
* [[Epicatechin gallate|ECG]]
* [[Epicatechin]]
* [[Hyperoside]]
* [[JDTic]]
* [[LY-255582]]
* [[LY-2196044]]
* [[LY-2444296]]
* [[LY-2459989]]
* [[LY-2795050]]<!--First KOR-selective antagonist radioligand; succeeded by LY-2459989-->
* [[MeJDTic]]<!--KOR-selective antagonist radiotracer-->
* [[Methylnaltrexone]]
* [[ML190]]
* [[ML350]]
* [[MR-2266]]
* [[N-Fluoropropyl-JDTic]]<!--KOR-selective antagonist radiotracer; brand new (2015)-->
* [[Naloxone]]
* [[Naltrexone]]
* [[Naltrindole]]
* [[Naringenin]]
* [[Norbinaltorphimine]]
* [[Noribogaine]]<!--Biased agonist-->
* [[Pawhuskin A]]
* [[PF-4455242]]
* [[RB-64]]<!--Biased agonist-->
* [[Quadazocine]]
* [[Taxifolin]]
* [[UPHIT]]<!--Irreversible-->
* [[Zyklophin]]

* '''Unknown/unsorted:''' [[Akuammicine]]
* [[Akuammine]]
* [[Coronaridine]]
* [[Cyproterone acetate]]
* [[Dihydroakuuamine]]
* [[Ibogamine]]
* [[Tabernanthine]]

 | group4 = {{abbrlink|NOP|Nociceptin receptor}}
 | list4 =
* '''Agonists:''' [[(Arg14,Lys15)Nociceptin]]
* [[((pF)Phe4)Nociceptin(1-13)NH2|((pF)Phe<sup>4</sup>)Nociceptin(1-13)NH<sub>2</sub>]]
* [[(Phe1Ψ(CH2-NH)Gly2)Nociceptin(1-13)NH2|(Phe<sup>1</sup>Ψ(CH<sub>2</sub>-NH)Gly<sup>2</sup>)Nociceptin(1-13)NH<sub>2</sub>]]
* [[Ac-RYYRWK-NH2|Ac-RYYRWK-NH<sub>2</sub>]]
* [[Ac-RYYRIK-NH2|Ac-RYYRIK-NH<sub>2</sub>]]
* [[BU08070]]
* [[Buprenorphine]]
* [[Cebranopadol]]
* [[Dihydroetorphine]]
* [[Etorphine]]
* [[JNJ-19385899]]
* [[Levomethorphan]]
* [[Levorphanol]]
* [[Levorphanol]]
* [[Lexanopadol]]
* [[MCOPPB]]
* [[MT-7716]]
* [[NNC 63-0532]]
* [[Nociceptin|Nociceptin (orphanin FQ)]]
* [[Nociceptin (1-11)]]
* [[Nociceptin (1-13)NH2|Nociceptin (1-13)NH<sub>2</sub>]]
* [[Norbuprenorphine]]
* [[Racemethorphan]]
* [[Racemorphan]]
* [[Ro64-6198]]
* [[Ro65-6570]]
* [[SCH-221510]]
* [[SCH-486757]]
* [[SR-8993]]
* [[SR-16435]]
* [[TH-030418]]

* '''Antagonists:''' [[(Nphe1)Nociceptin(1-13)NH2|(Nphe<sup>1</sup>)Nociceptin(1-13)NH<sub>2</sub>]]
* [[AT-076]]
* [[BAN-ORL-24]]
* [[J-113397]]
* [[JTC-801]]
* [[LY-2940094]]
* [[Naloxone benzoylhydrazone|NalBzOH]]
* [[Nociceptin (1-7)]]
* [[Nocistatin]]
* [[SB-612111]]
* [[SR-16430]]
* [[Thienorphine]]
* [[Trap-101]]
* [[UFP-101]]

 | group5 = Unsorted<!--In some cases, unknown-->
 | list5 =
* [[β-Casomorphin]]s
* [[Amidorphin]]
* [[BAM-20P]]<!--Very potent in guinea pig ileum assay-->
* [[Cytochrophin-4]]
* [[Deprolorphin]]
* [[Gliadorphin|Gliadorphin (gluteomorphin)]]
* [[Gluten exorphin]]s
* [[Hemorphin]]s
* [[Kava]] constituents<!--PMID: 11458444-->
* [[Met5-Enkephalin-Arg6,Phe7,Leu8|MEAGL]]
* [[Met5-Enkephalin-Arg6,Phe7|MEAP]]
* [[N-Ethylmaleimide|NEM]]<!--Irreversible-->
* [[Neoendorphin]]s
* [[Nepetalactone]] ([[catnip]])
* [[Peptide B]]
* [[Peptide E]]<!--Very potent in guinea pig ileum assay; verified KOR agonist-->
* [[Peptide F]]
* [[Peptide I]]
* [[Rubiscolin]]s
* [[Soymorphin]]s

 | group6 = Others
 | list6 =
* '''[[Enkephalinase inhibitor]]s:''' [[Amastatin]]
* [[BL-2401]]
* [[Candoxatril]]
* [[Phenylalanine#D-, L- and DL-phenylalanine|{{smaller|D }}-Phenylalanine]]
* [[Dexecadotril|Dexecadotril (retorphan)]]
* [[Ecadotril|Ecadotril (sinorphan)]]
* [[Kelatorphan]]
* [[Racecadotril|Racecadotril (acetorphan)]]
* [[RB-101]]
* [[RB-120]]
* [[RB-3007]]
* [[Opiorphan]]
* [[Selank]]
* [[Semax]]
* [[Spinorphin]]
* [[Thiorphan]]
* [[Tynorphin]]
* [[Ubenimex|Ubenimex (bestatin)]]

* '''Propeptides:''' [[β-Lipotropin|β-Lipotropin (proendorphin)]]
* [[Prodynorphin]]
* [[Proenkephalin]]
* [[Pronociceptin]]
* [[Proopiomelanocortin|Proopiomelanocortin (POMC)]]

* '''Others:''' [[Kyotorphin]] (met-enkephalin releaser/degradation stabilizer)

  | below = '''''See also:''' [[Template:Receptor modulators|Receptor/signaling modulators]] • [[Template:Signaling peptide/protein receptor modulators|Signaling peptide/protein receptor modulators]]''

}}<noinclude>
{{collapsible option}}
[[Category:Drug templates by receptor, channel, or pump]]
</noinclude>